Stereoselective Synthesis of Allylic Amines by One-Pot Tandem Reaction of Acetylenic Sulfone, Grignard Reagent, and N-Tosylimine

作者：Xie Mei hua^*; Sun Ying; Zhang Wei; Gu Xiao xia; Zhao Xin yang; Xie Fa dong; Wang Shao wu

来源：Synthetic Communications, 2008, 38(21): 3785-3796.

DOI：10.1080/00397910802226564

• Acetylenic sulfone
• allylic amine
• carbomagnesiation
• Grignard reagent
• N-tosylimine

Polysubstituted allylic amines were regio- and stereoselectively synthesized by a one-pot tandem reaction of Cu(I)-catalyzed carbomagnesiation of acetylenic sulfones and its further reaction with N-tosylimine.

• 出版日期2008
• 单位安徽师范大学