Dramatic response of a patient with pregnancy induced idiopathic pulmonary arterial hypertension to sildenafil treatment

作者：Tacoy Guelten^*; Ekim Numan Nadir; Cengel Atiye

来源：Journal of Obstetrics and Gynaecology Research, 2010, 36(2): 414-417.

DOI：10.1111/j.1447-0756.2009.01136.x

• idiopathic pulmonary arterial hypertension
• pregnancy
• sildenafil
• treatment

Idiopathic pulmonary arterial hypertension (IPAH) is characterized by a progressive increase in pulmonary vascular resistance, which may lead to right ventricular failure and death. Major cardiovascular and pulmonary alterations occur during pregnancy and therefore worsen or increase the complications of pulmonary arterial hypertension (PAH). A patient diagnosed with IPAH after a successful full-term pregnancy and cesarean section with epidural anesthesia is presented. The postoperative course was complicated by progressive dyspnea, and lower limb edema. The outcome of treatment with sildenafil during puerperium was favorable in this patient. The clinical course was complicated by an unexpected spontaneous pregnancy after primary infertility.

• 出版日期2010-4