A survey of female students with migraine: what is the influence of family history and lifestyle?

作者:Dzoljic Eleonora; Vlajinac Hristina*; Sipetic Sandra; Marinkovic Jelena; Grbatinic Ivan; Kostic Vladimir
来源:International Journal of Neuroscience, 2014, 124(2): 82-87.
DOI:10.3109/00207454.2013.823961

摘要

Objectives: To compare characteristics of migraine and some lifestyle habits in migraineurs with and without a positive family history for migraine. Method: The prevalence study was combined with a case-control study and comprised 245 female students with migraine. Results: Out of 245 female students with migraine, 132 (53.9%) had a positive family history for migraine. In comparison with migraineurs who had not, those with a positive family history were younger at the onset of migraine and significantly more frequently reported menstrual migraine (p < 0.001), unilateral pain (p < 0.05) and pulsate pain (p < 0.05) as well as severe headache (p < 0.01). In comparison to migraineurs with a positive family history for migraine, those who did not report a significantly higher frequency of average number of meals per day of < 3 (p < 0.001), missed meals (p < 0.05) and an average sleep duration of <= 6 h (p < 0.05). Conclusions: The results of the present study are in line with literature showing a high frequency of positive family history for migraine among migraineurs. They also suggest that subjects with a positive family history have a lower "migrainous threshold" for the development of migraine and that environmental factors are more important for the occurrence of migraine in subjects without a positive family history. Accordingly, the conclusions of this study are limited to reproductive aged women.