Amine-bridged binuclear complexes involving [Pd(ethylenediamine)(H2O)(2)](2+), 4,4 '-bipiperidine and DNA constituents

作者：Alla Perihan A Khalaf; Shoukry Mohamed M^*; van Eldik Rudi

来源：Journal of Coordination Chemistry, 2015, 68(12): 2041-2053.

DOI：10.1080/00958972.2015.1035263

• Palladium(II) complexes
• 4
• 4-bipiperidine
• DNA constituents
• Binuclear complexes
• Equilibrium constants

The complex formation equilibria in the reaction of [Pd(en)(H2O)(2)](2+) with 4,4-bipiperidine (Bip) and DNA constituents such as inosine, inosine-5-monophosphate, uracil, uridine, thymine, and thymidine were investigated at 25 degrees C and 0.1M ionic strength. The [(H2O)(en)Pd(Bip)Pd(en)(H2O)](4+) complex and its hydrolyzed species were formed. Substitution of coordinated water by inosine (Ino) as DNA constituent formed the complexes [(Ino)(en)Pd(Bip)Pd(en)(H2O)](3+) and [(Ino)(en)Pd(Bip)Pd(en)(Ino)](2+). The formation of the binuclear complexes was further supported by spectral measurements. The formation constants of all possible mono- and binuclear complexes were determined and their speciation diagrams were evaluated.

• 出版日期2015