A facile approach for the synthesis of 1,3-di-and 1,2,3-tri-substituted indolizines

作者：Tan Jun; Yang Yiwen^*; Chen Jie; Kuang Chunxiang

来源：Canadian Journal of Chemistry, 2015, 93(5): 542-545.

DOI：10.1139/cjc-2014-0494

• 1 ,2-dichloroethanes
• 1
• 2-dichloroethane
• High yield
• Indolizines
• Multi-component reactions
• Pyridinium salts

A convenient synthesis of 1,3-di-and 1,2,3-tri-substituted indolizines involving the multicomponent reaction of pyridinium salt (or quinolinium salt), olefine acid, and 1,2-dichloroethane has been achieved. The process proceeds smoothly in moderate to high yields.

• 出版日期2015
• 单位同济大学