Design and Synthesis of an Indole-Estrogen Derivative

作者：Lauro Figueroa Valverde^*; Francisco Diaz Cedillo; Marcela Rosas Nexticapa; Lenin Hau Heredia; Elodia Garcia Cervera; Eduardo Pool Gomez; Betty Sarabia Alcocer

来源：Journal of Chemistry, 2014, 2014: 460968.

DOI：10.1155/2014/460968

There are several methods reported for synthesis of aromatic-condensed derivatives; nevertheless, expensive reagents and special conditions are required. Therefore, in this study, an indole-estrogen derivative (3-[4-(2-butyl-3-cyclohexylimino-4-piperidin-1-yl-cyclobutylidencarbamoyl)]-phenoxy-NH-indolo[2',3': 17,16]estra-1,3,5(10)triene) was synthesized using some strategies. The structure of all compounds obtained was confirmed by spectroscopic and spectrometric methods. In conclusion, a facile procedure for the formation of an indole-estrogen derivative was developed in this study.

• 出版日期2014