Development of a pyrene based "turn on" fluorescent chemosensor for Hg2+

作者:Sivaraman Gandhi*; Anand Thangaraj; Chellappa Duraisamy
来源:RSC Advances, 2012, 2(28): 10605-10609.
DOI:10.1039/c2ra21202a

摘要

We have designed, synthesized, and evaluated a new pyrene-based "turn on" fluorescent chemosensor which showed remarkable enhanced fluorescence intensity in the presence of Hg2+ ions and a high selectivity towards Hg2+ ions over a wide range of metal ions in aqueous acetonitrile (ACN). The probe shows selectivity and sensitivity with a 12-fold enhancement in fluorescence towards Hg2+. Upon the addition of Hg2+ ions, the probe displayed an apparent color change, which could be observed by the naked eye under a UV lamp. It's in vitro sensitivity to Hg2+ was demonstrated in candida albicans cells with the use of confocal microscopy.

  • 出版日期2012