New Marine Antifouling Compounds from the Red Alga Laurencia sp.

作者:Oguri Yuko; Watanabe Mami; Ishikawa Takafumi; Kamada Takashi; Vairappan Charles S; Matsuura Hiroshi; Kaneko Kensuke; Ishii Takahiro; Suzuki Minoru; Yoshimura Erina; Nogata Yasuyuki; Okino Tatsufumi*
来源:Marine Drugs, 2017, 15(9): 267.
DOI:10.3390/md15090267

摘要

Six new compounds, omaezol, intricatriol, hachijojimallenes A and B, debromoaplysinal, and 11,12-dihydro-3-hydroxyretinol have been isolated from four collections of Laurencia sp. These structures were determined by MS and NMR analyses. Their antifouling activities were evaluated together with eight previously known compounds isolated from the same samples. In particular, omaezol and hachijojimallene A showed potent activities (EC50 = 0.15-0.23 mu g/mL) against larvae of the barnacle Amphibalanus amphitrite.

  • 出版日期2017-9