A pH-driven DNA switch based on the A(+)center dot G mispair

作者:Lee Jennifer A; DeRosa Maria C*
来源:Chemical Communications, 2010, 46(3): 418-420.
DOI:10.1039/b918725a

摘要

A new approach to the development of pH-driven DNA switches is presented. Here, the improved stability of the A center dot G mispair under slightly acidic conditions is exploited. The temperature tunability and the potential generality of the approach are discussed.

  • 出版日期2010