A novel non-enzymatic glucose sensor based on Pt3Ru1 alloy nanoparticles with high density of surface defects

作者：Yang, Jiangwei; Liang, Xinyi^*; Cui, Lan; Liu, Haiyan; Xie, Junbo; Liu, Weixing

来源：Biosensors and Bioelectronics, 2016, 80: 171-174.

DOI：10.1016/j.bios.2016.01.056

• Pt3Ru1 alloy nanoparticles
• Non-enzymatic sensor
• Glucose
• Surface defect

A novel non-enzymatic glucose sensor based on a glassy carbon electrode modified with Pt3Ru1 alloy nanoparticles (Pt3Ru1/GCE) was fabricated. Pt3Ru1 alloy nanoparticles were prepared by a reverse microemulsion method at room temperature. The X-ray diffraction (XRD) and energy dispersive X-ray spectroscopy (EDS) demonstrate that Pt3Ru1 nanoparticles are disordered alloy with face central cubic (fcc) structure and the atom ratio of Pt and Ru is 3:1. The high-resolution transmission electron microscopy (HRTEM) images show that Pt3Ru1 alloy nanoparticles were aggregated with a high density of surface defects. Furthermore, the sensor properties of Pt3Ru1/GCE were investigated by cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS) and chronoamperometry (CA) in 0.01 M PBS (pH 7.4). The results indicate that the proposed sensor exhibits a wide linear range of 5 x 10(-7) M to 10(-2) M (R-2=0.9988) with a low detection limit of 0.3 mu M for glucose. Moreover, the sensor demonstrates good sensitivity, stability, reproducibility, and better anti-interference performance toward ascorbic acid (AA), uric acid (UA), and fructose (Fru).

• 出版日期2016-6-15
• 单位天津大学; 天津商业大学