A Procedure for Facile Synthesis of Nucleosides Using N, O-Bistrimethylsilylacetamide in the Presence of Natural Phosphate Coated with Potassium Iodide

作者：Baddi Laila; Smietana Michael; Sebti Said; Vasseur Jean Jacques; Lazrek Hassan B^*

来源：Letters in Organic Chemistry, 2010, 7(3): 196-199.

• N-Glycosylation
• D/L nucleosides
• natural phosphate
• catalyst

Several alpha-D/L-arabino and beta-D/L- xylonucleosides were synthesized in good yields under mild conditions by N-glycosylation of 1-O-acetyl D/L- arabino, and xylofuranose, with silylated nucleobases (uracil, thymine and 6-azauracil) in acetonitrile using natural phosphate (NP) coated with potassium iodide in BSA as catalyst.

• 出版日期2010-4