An in-vitro animal experiment on metal implants' thermal effect on radiofrequency ablation

作者：Lin, Zhen-Wen; Chu, Hong^*; He, Fan; Wang, Lu-Ping; Kong, Jian

来源：World Journal of Surgical Oncology, 2013, 11(1): 147.

DOI：10.1186/1477-7819-11-147

• Implant
• Metal
• Radiofrequency ablation
• Thermal effect
• Animal experiment
• In vitro

Background: To explore metal implants' thermal effect on radiofrequency ablation (RFA) and ascertain distance-thermal relationship between the metal implants and radiofrequency (RF) electrode. @@@ Methods: Metal implants models were established in seven in-vitro porcine livers using silver clips or I-125 seeds. RFA were conducted centering the RF electrode axis1 cm away from them, with one side containing a metal implants model the test group and the other side the control group. The thermometric needles were used to measure multi-point temperatures in order to compare the time-distance-temperature difference between the two groups. The gross scopes of the ablation of the two groups were measured and the tissues were analyzed for microscopic histology. @@@ Results: At the ablation times of 8, 12, and 15 min, the average multi-point temperatures of the test group and the control group were 48.2 +/- 18.07 degrees C, 51.5 +/- 19.57 degrees C, 54.6 +/- 19.75 degrees C, and 48.6 +/- 17.69 degrees C, 52.2 +/- 19.73 degrees C, 54.9 +/- 19.24 degrees C, respectively, and the differences were not statistically significant (n=126, P>0.05). At the ablation times of 12 and 15 min, the ablation scopes of the test group and the control group were (horizontal/longitudinal diameter) 1.55/3.48 cm, 1.89/3.72 cm, and 1.56/3.48 cm, 1.89/3.72 cm, respectively, and the differences were not statistically significant (n=14, P>0.05). The two groups had the same manifestations in microscopy. @@@ Conclusions: Metal implants do not cause significant thermal effect on RFA.

• 出版日期2013-6-22
• 单位深圳市第二人民医院