Acinetobacter baumannii infections in a South African paediatric intensive care unit

作者：Reddy Deveshni; Morrow Brenda M^*; Argent Andrew C

来源：Journal of Tropical Pediatrics, 2015, 61(3): 182-187.

DOI：10.1093/tropej/fmv017

• nosocomial infection
• Acinetobacter baumannii
• ventilator-associated pneumonia
• infection control
• paediatric
• intensive care
• infectious disease

Objectives: To describe and compare characteristics and outcomes of patients colonized or infected with Acinetobacter baumannii (cases) to a control group.
Methods: A retrospective case-controlled study of patients admitted to a South African paediatric intensive care unit (PICU) between January and December 2010.
Results: Acinetobacter baumannii was isolated in 194 patients. Mortality was similar between cases (9.3%) and controls (9.8%). Median duration of PICU stay and mechanical ventilation in cases vs. controls was 10 vs. 2 (p< 0.0001) and 9 vs. 1 days (p< 0.0001), respectively. Admission diagnosis of traumatic brain injury [adjusted odds ratio (OR): 5.6, 95% CI: 1.2-27.0; p = 0.03] and duration of mechanical ventilation (adjusted OR: 1.4, 95% CI: 1.3-1.5; p< 0.0001) were independently associated with A. baumannii aquisition.
Conclusion: Acinetobacter baumannii acquisition was common and associated with increased morbidity, but not increased mortality.

• 出版日期2015-6