摘要

In this paper, a novel synthetic method of 1-hydrazinophthalazine hydrochloride was reported starting from cheap and easily accessible phthalic anhydride. The 1-hydrazinophthalazine hydrochloride could be obtained by reduction, bromination, cyclization, substitution and acidification separately. The results showed that the advantages of this method were simply available starting materials, relatively high yield, easily purification of the product and low cost.