Diagnostic, stratification du risque rythmique et prise en charge du syndrome de Brugada

作者：Gourraud Jean Baptiste^*; Barc Julien; Thollet Aurelie; Le Marec Herve; Probst Vincent

来源：Archives of Cardiovascular Diseases, 2017, 110(3): 188-195.

DOI：10.1016/j.acvd.2016.09.009

• Brugada syndrome
• Prognosis
• Diagnosis
• Sudden cardiac death
• Risk stratification

Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific electrocardiogram pattern, observed either spontaneously or during a sodium channel blocker test. Among affected patients, risk stratification remains a challenge, despite recent insights from large population cohorts. As implantable cardiac defibrillators the main therapy in Brugada syndrome are associated with a high rate of complications in this population, the main challenge is risk stratification of patients with Brugada syndrome. Aside from the two main predictors of arrhythmia (symptoms and spontaneous electrocardiogram pattern), many risk factors have been recently suggested for stratifying risk of sudden cardiac death in Brugada syndrome. We have reviewed these data and discuss current guidelines in light of recent progress in this complex field.

• 出版日期2017-3