A case of dermatopathia pigmentosa reticularis with wiry scalp hair and digital fibromatosis resulting from a recurrent KRT14 mutation

作者：Goh B K^*; Common J E A; Gan W H; Kumarasinghe P

来源：Clinical and Experimental Dermatology, 2009, 34(3): 340-343.

DOI：10.1111/j.1365-2230.2008.02950.x

We report a patient of Malay ancestry with dermatopathia pigmentosa reticularis (DPR) resulting from a recurrent KRT14 p.R125C mutation. The patient has reticulate hyperpigmentation over his trunk and proximal limbs, together with onychodystrophy. Despite the absence of noncicatricial alopecia, he has acral nonscarring blisters, palmoplantar hyperkeratosis and hypoplastic dermatoglyphics, in addition to unusual abnormalities such as wiry scalp hair and digital fibromatous thickening.

• 出版日期2009-4
• 单位河北医科大学