Advances in understanding cis regulation of the plant gene with an emphasis on comparative genomics

作者：Burgess Diane G; Xu Jie; Freeling Michael

来源：Current Opinion in Plant Biology, 2015, 27: 141-147.

DOI：10.1016/j.pbi.2015.07.001

The plant gene model remains largely an extrapolation from animals, with the cis functional unit, the gene, cast as a dynamic looping structure. Molecular genetics with model plants continues to make advances; highlighted here are quantitative-occupancy results from the Arabidopsis thaliana (Arabidopsis) Phytochrome-Interacting bHLH transcription Factors (PIF) quartet. Compared to this complex snapshot, results from chromatin occupancy and other Encyclopedia of DNA Elements (ENCODE)-like approaches increase our transcription factor-motif cognate library, but regulation cannot by itself be inferred from binding. Complementary published Arabidopsis conserved noncoding sequence lists are compared, evaluated, merged, and released. Comparative genomic approaches have identified a cis modifier of a gene's expression - hypothetically, a transposon-based 'rheostat' - that works in all cells, times and places.

• 出版日期2015-10
• 单位四川农业大学