An alternate synthesis of levetiracetam

作者：Mylavarapu Ravikumar; Anand Ramasamy Vijaya; Kondaiah Golla China Mala; Reddy Lekkala Amarnath; Reddy Gade Srinivas; Roy Arnab; Bhattacharya Apurba; Mukkanti Kagga; Bandichhor Rakeshwar^*

来源：Green Chemistry Letters and Reviews, 2010, 3(3): 225-230.

DOI：10.1080/17518251003716568

• solvent-free condensation
• metal-catalyzed oxidation
• amidation
• levetiracetam

Development of a new strategy for the synthesis of levetiracetam 1 is described. This strategy involves solvent-free condensation, metal-catalyzed oxidation, and amidation. Solvent-free condensation and metal-catalyzed oxidation make this synthesis a more eco-friendly alternative for the synthesis of levetiracetam.
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• 出版日期2010