An unexpected copper-catalyzed carbonylative acetylation of amines

作者:Li Yahui; Wang Changsheng; Zhu Fengxiang; Wang Zechao; Soule Jean Francois; Dixneuf Pierre H; Wu Xiao Feng*
来源:Chemical communications, 2017, 53(1): 142-144.
DOI:10.1039/c6cc08929a

摘要

A novel copper-catalyzed carbonylative acetylation of amines has been developed. With peroxide as the oxidant as well as the methyl source with a copper catalyst under CO pressure, good yields of N-acetyl amides could be obtained. Notably, this is the first example of carbonylative acetylation.

  • 出版日期2017