Activated Carbon Adsorbent for the Aqueous Phase Adsorption of Amoxicillin in a Fixed Bed

作者：Ornelas Nuno J R; Aguiar Cynara R; Moraes Suelena M O; Adriano Wellington S; Goncalves Luciana R B^*

来源：Chemical Engineering & Technology, 2010, 33(4): 658-663.

DOI：10.1002/ceat.200900424

• Adsorption
• Amoxicillin
• Activated carbon
• 6-aminopenicillanic acid

Equilibrium constant and mass transfer parameters are needed for the study of amoxicillin separation in any process involving adsorption in fixed beds. In this work, the adsorption of amoxicillin and 6-aminopenillanic acid in aqueous solution on activated carbon were studied using static adsorption tests. The adsorption capacity was found to be strongly dependent on the pH of the aqueous phase. The adsorption constants, overall mass transfer coefficients, and axial dispersion coefficients for amoxicillin and 6-aminopenillanic acid were determined, by moment analysis, from a series of step tests in a fixed bed packed with activated carbon. The total bed voidage and axial dispersion coefficient were estimated from blue dextran pulse test data at different flow rates. The results show that adsorption intensity increased with increasing temperature. Furthermore, the increasing trend of HETP with velocity suggests that axial dispersion and mass transfer resistance control the column efficiency.

• 出版日期2010-4