A selective molecularly imprinted polymer-carbon nanotube sensor for cotinine sensing

作者：Antwi Boampong Sadik; Mani Kristina S; Carlan Jean; BelBruno Joseph J^*

来源：Journal of Molecular Recognition, 2014, 27(1): 57-63.

DOI：10.1002/jmr.2331

• molecularly imprinted polymer
• conductive sensor
• cotinine
• carbon nanotube composite
• poly-4-vinylphenol
• thin films

Conductive composite films comprised of single-walled carbon nanotubes coated with molecularly imprinted poly-4-vinylphenol are produced and characterized using ultraviolet and infrared spectroscopies, confirming the successful molecular imprinting of the film with cotinine. The electrical resistance of the imprinted film changes significantly upon binding cotinine, by more than 30k, while the unimprinted film in comparison elicits little response. Additionally, once the cotinine template desorbs from the film, the resistance of the imprinted film returns to a value close to the pre-adsorption baseline. Scanning electron microscopy is used to study the morphology of the film compared with the unimprinted control, and gas chromatography quantitatively confirms that the imprinted film selectively detects cotinine while discriminating against the structurally similar alkaloid, nicotine.

• 出版日期2014-1