A chemical epigenetics approach for engineering the in situ biosynthesis of a cryptic natural product from Aspergillus niger

作者:Henrikson Jon C; Hoover Ashley R; Joyner P Matthew; Cichewicz Robert H
来源:Organic and Biomolecular Chemistry, 2009, 7(3): 435-438.
DOI:10.1039/b819208a

摘要

A new fungal metabolite, nygerone A (1), featuring a unique 1-phenylpyridin-4(1H)-one core that had previously not been reported from any natural source, has been obtained from Aspergillus niger using a chemical epigenetics methodology.

  • 出版日期2009