Limb Development: The Rise and Fall of Retinoic Acid

作者：Lewandoski Mark^*; Mackem Susan

来源：Current Biology, 2009, 19(14): R558-R561.

DOI：10.1016/j.cub.2009.06.017

Retinoic acid was thought to play a key instructive role during limb bud initiation and subsequent patterning. New results argue instead that its role is permissive: retinoic acid is essential only to antagonize early axial Fgf signals that otherwise inhibit the limb field.

• 出版日期2009-7-28