A New Histone at the Centromere?

作者:Foltz Daniel R; Stukenberg P Todd*
来源:Cell, 2012, 148(3): 394-396.
DOI:10.1016/j.cell.2012.01.023

摘要

The centromere is a classic system to study epigenetic specification, and most research has focused on a specialized histone variant, CENP-A, that is required for kinetochore assembly. Now Nishino et al. reveal a new level of complexity for centromeric chromatin, by showing that the kinetochore complex CENP-T-W-S-X shares structural and functional properties with canonical histones.

  • 出版日期2012-2-3