A New 1 '-Methylenedisulfide Deoxyribose that Forms an Efficient Cross-nk to DNA Cytosine-5 Methyltransferase (DNMT)

作者：Shigdel Uddhav Kumar; He Chuan^*

来源：Journal of the American Chemical Society, 2008, 130(52): 17634-+.

DOI：10.1021/ja8064304

A newly designed 1'-methylenedisulfide deoxyribose probe can efficiently cross-link to DNA cytosine-5-methyltransferases (DNMTs) through the active Cys residue, which provides a new toot to covalently trap DNMT-DNA complexes.

• 出版日期2008-12-31