Dose Targeting Metrics in Conventional and Intensive Maintenance Dialysis

作者:Ananthakrishnan Shubha; Depner Thomas A
来源:Seminars in Dialysis, 2016, 29(6): 471-475.
DOI:10.1111/sdi.12526

摘要

Hemodialysis has come a long way since its early days and is a life sustaining therapy for millions of people with end-stage kidney disease throughout the world. Although thrice weekly hemodialysis remains the most common form of renal replacement therapy, other therapies such as more frequent, prolonged dialysis modalities have seen a rise recently. In this review, we compare and contrast methods for measuring the dialysis dose, with a focus on small molecule clearance (Kt/V-urea) among various dialysis modalities. We also describe newer on-line methods to measure dialysis and limitations to current adequacy measurement. Distinguishing dialysis adequacy from adequate treatment of the patient is also emphasized.

  • 出版日期2016-12