An efficient and green oxidation of vicinal diols to aldehydes using polymer-supported (diacetoxyiodo)benzene as the oxidant

作者：Chen Fen Er^*; Xie Bin; Zhang Ping; Zhao Jian Feng; Wang Hui; Zhao Lei

来源：Synlett, 2007, 2007(4): 619-622.

DOI：10.1055/s-2007-970745

• polymer-supported (diacetoxyiodo)benzene
• vicinal diols
• oxidative cleavage
• aldehydes

An operationally simple and clean oxidation of a variety of vicinal diols to aldehydes using polymer-supported (diacetoxyiodo)benzene (PSDIB) has been developed in high to excellent yields. Protecting groups such as OAc, OR, OBn, OBz and isopropylidene in the substrates were found to be stable under these reaction conditions. The regenerated PSDIB could be reused for the same reaction, affording oxidation products in high yield and purity.

• 出版日期2007-3-1
• 单位复旦大学