摘要

RHD virus (RHDV), which causes rabbit hemorrhagic disease, is the object of phylogenetic studies. The results of these studies provide valuable information on this pathogen. The purpose of present review is to summarize current knowledge about the phylogenetic position of this virus. The paper discusses the results of previous phylogenetic studies of RHDV, including factors affecting the shape of the phylogeny of this species and the diversity of RHDV strains in different parts of the world. It also presents the results of phylogenetic analysis of RHDV enriched with non-pathogenic and low pathogenic strains of rabbit lagoviruses, as well as phylogenetic analyses performed using modern Bayesian methods. The paper also highlights the unclear situation of Lagovirus taxonomy and shows selected data on the evolution of RHDV, gathered using phylogenetic methods. Finally, the possibility of using rabbit lagoviruses as a model for the study of the evolution of mammalian ssRNA(+) viruses has been shown.

  • 出版日期2015-1