A water-soluble fluorescent probe for ClO- and Cd2+ under physiological pH and its applications in living cells imaging

作者：Ma, Pinyi; Zhang, Bo; Diao, Quanping; Li, Lin; Sun, Ying; Wang, Xinghua; Song, Daqian^*

来源：Sensors and Actuators B: Chemical , 2016, 233: 639-645.

DOI：10.1016/j.snb.2016.04.142

• Fluorescence probe
• Fluorescein
• Water-soluble
• ClO-
• Cd2+
• Living cells

A water-soluble fluorescence probe (TF) derived from fluorescein has been developed. This probe can be used to detect ClO- and Cd2+ under physiological condition based on oxidation and coordination reactions, exhibiting almost 64-fold and 4-fold fluorescence enhancement. The experimentally observed changes in the structure and electronic properties of the probe in the presence of ClO- and Cd2+ were modeled by density functional theory (DFT) and time-dependent density functional theory (TDDFT) computational calculations. Moreover, the present probe was successfully applied to the fluorescence imaging of ClO- and Cd2+ in living cells.

• 出版日期2016-10-5
• 单位吉林大学; 鞍山师范学院