Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury

作者：Malhotra A^*; Fahey M C; Davies Tuck M; Wong F; Carse E; Whiteley G; Ditchfield M

来源：Journal of Perinatology, 2017, 37(7): 864-868.

DOI：10.1038/jp.2017.39

OBJECTIVE: To compare information obtained from preterm magnetic resonance imaging (MRI; 31-34 weeks) brain scan to that done at term equivalent age.
STUDY DESIGN: Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.
RESULTS: Fourteen infants with a median (range) gestation at birth of 28 (25-29) weeks and birth weight of 1254 (680-1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman p=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9-0.94). There was also a high level of agreement between the preterrn and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53-0.94)).
CONCLUSIONS: Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.

• 出版日期2017-7
• 单位河北医科大学