Fast identification of flavonoids in the roots of Sophora flavescens by on-flow LC-NMR

作者：Kim Su Jin; Kim Sang Min; Kim Min Cheol; Kang Suk Woo; Um Byung Hun^*

来源：Journal of Medicinal Plants Research, 2010, 4(23): 2452-2459.

• LC-hyphenated
• on-flow LC-NMR
• prenyl-flavonoid
• Sophora flavescens

Sophora flavescens Ait (Leguminosae) is a Chinese herbal medicine. Sophorae radix, the dried roots of S. flavescens, has been used for various diseases including atherosclerosis and arrhythmias. For the direct identification of the compounds present in Sophorae radix, the hyphenated LC-NMR technique has been applied. WET solvent suppression and scout scan techniques were used to suppress solvent peaks in on-flow LC-NMR experiment. Six prenylflavonoids were identified successfully as kushenol U (1), kurarinone (2), sophoraflavanone G (3), leachianone A (4), kuraridin (5) and kushenol A (6).

• 出版日期2010-12-4