A case of acute metronidazole neurotoxicity in cat

作者:Masucci Marisa*; De Majo Massimo; Malara Daniela; Lombardo Gabriella; Privitera Linda; Pennisi Maria Grazia
来源:Veterinaria, 2010, 24(5): 57-60.

摘要

A cat with chronic renal failure received two 125 mg/kg doses PO q12 of metronidazole. One hour after the second dose the animal experienced acute onset of neurological signs: disorientation, deafness, ataxia, generalized weakness, hypo/analgesia in the extremities and hyperesthesia in the head. The neurological abnormalities improved dramatically within 24 hours after discontinuing metronidazole, except for a brief seizure, and initiating supportive therapy and resolved gradually in about 2 months.

  • 出版日期2010-10