Muscle-specific kinase antibody associated myasthenia gravis after bone marrow transplantation

作者：Heidarzadeh Zeinab; Mousavi Seyyed Asadollah; Ostovan Vahid Reza; Nafissi Shahriar^*

来源：Neuromuscular Disorders, 2014, 24(2): 148-150.

DOI：10.1016/j.nmd.2013.11.005

• Myasthenia gravis
• Muscle-specific kinase antibody
• Allogeneic bone marrow transplant
• Graft-versus-Host Disease

Myasthenia gravis is a rare complication of bone marrow transplantation and graft versus host disease. We report a 30-year-old woman presented with oculobulbar and proximal limb weakness after allogeneic bone marrow transplantation for chronic myelogenous leukemia. Also, she developed graft versus host disease following bone marrow transplantation. Investigations led to the diagnosis of muscle specific kinase antibody related myasthenia gravis. There have been only two case reports of muscle specific kinase antibody positive myasthenia gravis after bone marrow transplantation in the literature, but none of the previously reported cases had graft versus host disease.

• 出版日期2014-2