A Novel Approach for Studying Histone H1 Function in Vivo

作者：Siriaco Giorgia; Deuring Renate; Mawla Gina D; Tamkun John W

来源：GENETICS, 2015, 200(1): 29-33.

DOI：10.1534/genetics.114.170514

• Drosophila
• histone H1
• chromatin
• gene expression

In this report, we investigate the mechanisms that regulate Drosophila histone H1 expression and its association with chromatin in vivo. We show that histone H1 is subject to negative autoregulation and exploit this result to examine the effects of mutations of the main phosphorylation site of histone H1.

• 出版日期2015-5