Depression, Stress, and Weight Loss in Individuals with Metabolic Syndrome in SHINE, a DPP Translation Study

作者：Trief Paula M^*; Cibula Donald; Delahanty Linda M; Weinstock Ruth S

来源：Obesity, 2014, 22(12): 2532-2538.

DOI：10.1002/oby.20916

ObjectiveTo examine the relationships between elevated depression symptoms (EDS) or stress and weight loss in SHINE, a telephonic, primary-care based, translation of the Diabetes Prevention Program. %26lt;br%26gt;MethodsN=257 adults with metabolic syndrome were randomized to individual (IC) or group (CC) phone participation. Weight, depression, anti-depressant use (ADMs), and stress (baseline, 6 months, 1 and 2 years) were assessed. Univariate analyses used linear and logistic regression, t tests for continuous variables and exact tests for categorical variables. Stratified analyses assessed modifiers of effects of depression/stress on weight loss. %26lt;br%26gt;ResultsApproximately 35% reported EDS, with no change over time. Approximately 28% of all participants used ADMs. Participants with EDS had lower mean % weight loss and a smaller % who achieved 5% weight loss. Participants with EDS were less likely to be completers (40.1% vs. 61.5%, P=0.002), coached (48.0% vs. 60.7%, P=0.049), or log diet/activity (19.4% vs. 42.7%, P%26lt;0.001), behaviors related to weight loss. Results were similar for high stress. ADM use had no independent effect on weight loss. %26lt;br%26gt;ConclusionsIndividuals with metabolic syndrome and EDS and/or high stress were less likely to lose significant weight. Pre-intervention depression and stress screening to intervene may improve weight loss.

• 出版日期2014-12