A modified cyclen azaxanthone ligand as a new fluorescent probe for Zn2+

作者：Nouri Hela; Cadiou Cyril^*; Lawson Daku Latevi Max; Hauser Andreas; Chevreux Sylviane; Dechamps Olivier Isabelle; Lachaud Fabien; Ternane Riadh; Trabelsi Ayadi Malika; Chuburu Francoise; Lemercier Gilles

来源：Dalton Transactions, 2013, 42(34): 12157-12164.

DOI：10.1039/c3dt51216a

A new cyclen derivative L, bearing a methyl-chromeno-pyridinylidene hydrazone moiety, was synthesized and studied in MeOH, as potential fluorescent %26quot;OFF-on-ON%26quot; sensors for Zn(II). Photophysical properties of this ligand being PET regulated, L was only weakly emissive in the absence of metal ions (OFF). L fluorescence was increased modestly upon addition of one equivalent of Zn(II), and further increased upon addition of a second equivalent. Therefore, Zn : L behaved as a highly sensitive ON sensor for zinc. This efficiency was correlated to Zn(II) coordination via the hydrazone moiety of the fluorophore, producing an efficient CHelation-Enhanced Fluorescence (CHEF) effect. A complementary theoretical study carried out with DFT calculations further elucidated the optical properties.

• 出版日期2013