A one-pot approach to 4,5-dihydropyrazoles from ketones, arylacetylenes, and hydrazines

作者：Wang, Ying-Chun; Wang, Heng-Shan^*; Huang, Guo-Bao; Huang, Fu-Ping; Hu, Kun; Pan, Ying-Ming

来源：Tetrahedron, 2014, 70(8): 1621-1628.

DOI：10.1016/j.tet.2014.01.021

• 4,5-Dihydropyrazoles
• Ketones
• Arylacetylenes
• Hydrazines
• Tandem reactions

An efficient and straightforward one-pot strategy for the synthesis of 4,5-dihydropyrazole derivatives from ketones, arylacetylenes, and hydrazines in the presence of (KOBu)-Bu-t/DMSO is described. This strategy provides a flexible and rapid route to polysubstituted 4,5-dihydropyrazoles.

• 出版日期2014-2-25
• 单位吉首大学; 广西师范大学