An efficient fluorination of beta-ketosulfones promoted by a room-temperature ionic liquid at ambient conditions under ultrasound irradiation using Selectfluor (TM) F-TEDA-BF4

作者：Heravi Mohammad Reza Poor^*

来源：Chinese Chemical Letters, 2010, 21(12): 1399-1402.

DOI：10.1016/j.cclet.2010.06.030

• Fluorination
• Ultrasound irradiation
• beta-Ketosulfones
• Selectfluor (TM)
• Ionic liquids (ILs)

The fluorination reaction involving a beta-ketosulfones by Selectfluor (TM) was efficiently promoted by the ionic liquid, [Hbim]BF4 (IL) as a reaction medium with methanol as co-solvent at room temperature under ultrasonic irradiation to afford the corresponding mono and difluoro-beta-ketosulfones in excellent yields. The advantages of this method include among others the use of a recyclable, non-volatile ionic liquid, which promotes this protocol under room temperature without the requirement of any added catalyst under ultrasonic irradiation.

• 出版日期2010-12