摘要

Aim. To explore the 6D registration marker and method for patients with esophageal cancer after CBCT scan. Materials and methods. 30 groups of CBCT images were acquired before IGRT and the corresponding planning CT images of esophageal cancer were chosen. We defined and contoured registration markers which would be used for 6D image registration. With the reference of manual match, bone match, grey value match, manual match and bone plus manual match were compared. Results. 1) For patients with esophageal cancer, the application of registration marker could make the 6D registration before IGRT quick and precise; 2) Compared with manual match, two statistical differences in bone match and bone match plus manual match and 4 statistical differences in grey value match were present; 3) The coincidence rate of bone match plus manual was the highest, and the results of bone match and grey value match were similar; 4) The compared result of registration time: manual match> bone plus manual match> grey value match> bone match. Conclusions. The registration of patients with esophageal cancer before IGRT needs registration marker. Bone match plus manual is the best registration method for registration time and accuracy. Eur. J. Oncol., 17 (3), 135-139, 2012