Movin' on through with Cdc2

作者:Juliano R*
来源:Nature Cell Biology, 2003, 5(7): 589-590.
DOI:10.1038/ncb0703-589

摘要

Proteins that control the cell cycle would seem to have little to do with cell migration. However, a recent report indicates that Cdc2, a key cyclin-dependent kinase, can also enhance cell migration. Levels of Cdc2 are upregulated in cells that express high levels of the alpha(v)beta(3) integrin, a protein that has long been implicated in enhanced migration and invasion of tumour cells.

  • 出版日期2003-7