Assessing two methods of repair of duodenal defects, jeujenal serosal patch and jejunal pedicled flap, (an experimental animal study)

作者：Ziaian Bizhan; Hosseinzadeh Massood; Nikravesh Behroz; Roshanravan Reza; Rahimikazerooni Salar; Safarpour Ali Reza; Moslemi Sam

来源：Journal of Pakistan Medical Association, 2014, 64(8): 907-910.

• Duodenal injury
• Wound healing
• Experimental study
• Surgery

Objective To evaluate the outcomes of jejunal serosal patch and jejunal pedicled flap procedures for the repair of duodenal injuries %26lt;br%26gt;Methods The experimental animal model study was conducted at Shiraz University of Medical Sciences Iran in February 2013 Ten mixed breed male dogs were selected and randomly divided into groups A and B After general anaesthesia a large duodenal defect was created in all animals The defect was repaired with jejunal pedicled flap in group A and jejunal serosal patch in group B Microscopic healing was scored according to epithelialisation collagenisation inflammation ulcer and necrosis of samples Kolmogorov Smirnov and independent t test were used to indicate normal distributions of data and statistical differences between the two groups respectively %26lt;br%26gt;Results The weight of the animals ranged between 23 and 37kg and the age range was 12 16 months All dogs survived the procedures Anastomotic leakage intra abdominal abscess or intestinal obstructions were not detected in gross examination Healing score was significantly higher in the group A than group B (p%26lt;0 011) However in terms of surgical findings no significant difference was detected between the groups (p%26gt;0 05) %26lt;br%26gt;Conclusion Applying jejunal pedicled flap for repairing large duodenal defects would lead to better histologic outcomes compared to jejunal serosal patch in dogs

• 出版日期2014-8