Diffuse systemic sclerosis with bullous lesions without systemic manifestations

作者：Wanderley Caratta Macedo Paula Renaux; Cavalleiro de Macedo Mota Amanda Nascimento; Gripp Alexandre Carlos; Guimaraes Scotelaro Alves Maria de Fatima; Klumb Evandro Mendes

来源：Anais Brasileiros de Dermatologia, 2013, 88(6): 78-81.

DOI：10.1590/abd1806-4841.20132160

• Connective tissue diseases
• Scleroderma, diffuse
• Scleroderma, systemic
• Skin diseases, vesiculobullous
• Skin and connective tissue diseases

Here, we describe an atypical case of systemic sclerosis in its diffuse cutaneous form with acute and rapid progression of the cutaneous condition, without any systemic manifestations and the infrequent formation of bullae, showing the importance of diagnosis and early treatment in such cases. This case also shows that special measures should be taken for bullous cutaneous lesions and ulcerations resulting from serious sclerosis, which are entry points and increase morbidity and risk of death. Other prognostic factors include age, ESR and renal and pulmonary involvement. Capillaroscopies can be useful predictors of greater severity of systemic scleroderma, revealing a greater link with systemic, rather than cutaneous, involvement.

• 出版日期2013-12