DEEP BRAIN STIMULATION FOR TREATMENT REFRACTORY OBSESSIVE-COMPULSIVE DISORDER - A CASE REPORT

作者：Csigo Katalin^*; Dome Laszlo; Harsanyi Andras; Demeter Gyula; Racsmany Mihaly

来源：Ideggyogyaszati Szemle-Clinical Neuroscience, 2010, 63(3-4): 137-142.

• treatment refractory obsessive-compulsive disorder
• deep brain stimulation
• neuropsychology
• executive functions

In the last 30 years it has been a great development in the understanding and therapy of obsessive-compulsive disorder. Adequate pharmaco- and cognitive-behavior therapies reduce the symptoms in 40-60% of patients, so a remarkable portion of patients still remains refractory to conventional treatment. Neurosurgery with it's reversible and irreversible techniques brought a breakthrough in the therapy of treatment refractory patients. In the present case, we represent a 3 months follow-up of an obsessive-compulsive patient treated by deep brain stimulation. In our case, the stimulation target was the anterior limb of internal capsule. The clinical symptoms were measured by Y-BOCS. In addition various neuropsychological tests were used to monitor patient's executive functions before and 3 months after the deep brain stimulation. We found that obsessive-compulsive symptoms improved after three months of the stimulation. The neuropsychological tests showed improvement in some executive functions (e.g. fluency, set-shifting, decision making). On the other hand our results revealed severe neurocognitive - mainly attention skill deficits in a treatment refractory obsessive-compulsive patient.

• 出版日期2010-3-30