摘要

In this review, I describe the biological applications of the atomic force microscope (AFM). The historical background and the development of the microscope are described. The AIM can operate in many different modes relevant to biological systems including topography, chemical analysis, and forces relevant at the biological length scale (single cell to DNA dimensions and pico to nano Newton forces). A limited number of examples from the literature are described to illustrate some of the many capabilities of this microscope. The aim is to give an introduction of the technique to the inexperienced in this rapidly growing field.

  • 出版日期2006-6