BAAQ: An infrastructure for application integration and knowledge discovery in Bioinformatics

作者：Gong Xiujun^*; Nakamura Kensuke; Yu Hua; Yura Kei; Go Nobuhiro

来源：IEEE Transactions on Information Technology in Biomedicine, 2007, 11(4): 428-434.

DOI：10.1109/TITB.2006.888700

• active solution recommendation (ASR)
• bioinformatics
• grid application
• task mapping editor (TME)

The emerging grid computing technologies enable bioinformatics scientists to conduct their researches in a virtual laboratory, in which they share public databases, computational tools as well as their analysis workflows. However, the development of grid applications is still a nightmare for general bioinformatics scientists, due to the lack of grid programming environments, standards and high-level services. Here, we present a system, which we named Bioinformatics: Ask Any Questions (BAAQ), to automate this development procedure as much as possible. BAAQ allows scientists to store and manage remote biological data and programs, to build analysis workflows that integrate these resources seam-lessly, and to discover knowledge from available resources. This paper addresses two issues in building grid applications in bioinformatics: how to smoothly compose an analysis workflow using heterogeneous resources and how to efficiently discover and re-use available resources in the grid community. Correspondingly an intelligent grid programming environment and an active solution recommendation service are proposed. Finally, we present a case study applying BAAQ to a bioinformatics problem.

• 出版日期2007-7
• 单位天津大学