A new and convenient synthesis of phendiones oxidated by KBrO3/H2SO4 at room temperature

作者:Zheng, Ren Hua; Guo, Hai Chang; Jiang, Hua Jiang; Xu, Ke Hui; Liu, Bei Bei; Sun, Wei Lin*; Shen, Zhi Quan
来源:Chinese Chemical Letters, 2010, 21(11): 1270-1272.
DOI:10.1016/j.cclet.2010.05.030

摘要

A new method is described to synthesize phendione derivatives from 1,10-phenanthrolines using potassium bromate and 60% sulfuric acid as oxidant, which was easily applicable to scale-up. The reaction conditions are mild and the yields are excellent. The target compounds have been characterized by H-1 NMR, and IR.