A new cytotoxic cardenolide from the latex of Antiaris toxicaria

作者：Gan, Yu Juan; Mei, Wen Li^*; Zhao, You Xing; Dai, Hao Fu

来源：Chinese Chemical Letters, 2009, 20(4): 450-452.

DOI：10.1016/j.cclet.2008.12.043

• Antiaris toxicaria
• Moraceae
• Toxicarioside E
• Cardenolide
• Cytotoxicity

A new cardenolide, toxicarioside E (1), was isolated from the latex of Antiaris toxicaria (Pers.) Lesch (Moraceac). Its structure was elucidated on the basis of spectral data and chemical evidence. Compound 1 showed significant cytotoxicity against K562 and SGC-7901 cell lines in vitro by MTT method with the IC50 value of 0.026 and 0.027 mu g/mL, respectively.

• 出版日期2009-4
• 单位中国科学院昆明植物研究所; 中国热带农业科学院