A novel method for the synthesis of 1,2-benzisoxazoline-3-one and its application to hypochlorite recognition

作者:Yang, Yutao; Huo, Fangjun; Yin, Caixia*; Xu, Ming; Hu, Ying; Chao, Jianbin; Zhang, Yongbin; Glass, Timothy E.*; Yoon, Juyoung*
来源:Journal of Materials Chemistry B, 2016, 4(30): 5101-5104.
DOI:10.1039/c6tb01392a

摘要

The reaction of salicylhydroxamic acid with hypochlorite produces 1,2-benzisoxazoline-3-one, a heterocycle that contains a fluorophore. As a result, this reaction was used as the basis for a new, selective and sensitive fluorescence system for the recognition of hypochlorite. The effectiveness of the method was demonstrated by its use to detect hypochlorite in a disinfectant solution as well as to image hypochlorite in cells.