A new cyclopeptide from Clausena anisum-olens

作者:Wang YS; He HP; Yang JH; Shen YM; Zhou J; Hao XJ*
来源:Helvetica Chimica Acta, 2005, 88(8): 2345-2348.
DOI:10.1002/hlca.200590169

摘要

A new cyclopeptide, clausenain I (1), has been isolated by a multi-step chromatography procedure from Clausena anisum-olens. Its structure was elucidated as cyclo (-Gly(1)-Ile(2)-Ile(3)-Val(4)-Leu(5)-Ile(6)-Ile(7)-Leu(8)-Leu(9)-) by extensive 2D-NMR spectroscopic methods and chemical evidence. It is the first time that a natural cyclic peptide has been isolated from the genus Clausena.