A sub-nanomole level electrochemical method for determination of prochloraz and its metabolites based on medical stone doped disposable electrode

作者：Li Hongbo; Li Jing; Hou Chuantao; Du Shi; Ren Yanyan; Yang Zhanjun; Xu Qin; Hu Xiaoya^*

来源：Talanta, 2010, 83(2): 591-595.

DOI：10.1016/j.talanta.2010.10.002

• Prochloraz
• 2,4,6-Trichlorophenol
• Medical stone
• Electroanalysis
• Disposable electrode

A ultrasensitive, simple and convenient electrochemical method was firstly developed for the determination of prochloraz and its metabolites as 2.4,6-trichlorophenol (2,4,6-TCP) using nano-aperture medical stone. Compared with the uncloped disposable electrode (UDE), nano-aperture medical stone doped disposable electrode (MSDDE) not only significantly enhances the oxidation peak current of 2,4,6-TCP but also lowers the oxidation overpotential, suggesting that the nano-aperture MSDDE can remarkably improve the sensitivity of 2,4,6-TCP. The experimental conditions such as pH values of buffer solution, the content of nano-aperture medical stone, accumulation potential and time were optimized for the determination of 2,4,6-TCP. At optimal conditions, the oxidation peak current is proportional to the concentration of 2,4,6-TCP over the range from 6.0 x 10(-9) to 8.0 x 10(-5) mol L. Finally, this novel method was successfully employed to detect prochloraz and its metabolites in orange rind with the detection limit of 8.4 x 10(-10) mol L(-1) (0.3 ngg(-1)) and the method was validated by gas chromatography.

• 出版日期2010-12-15
• 单位扬州大学; 盐城工学院